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Effects of early- and mid-life stress on DNA methylation of genes associated with subclinical cardiovascular disease and cognitive impairment: a systematic review

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Subgroup and sensitivity analyses In subgroup analysis, new AHM users (initiated after January 1, 2011, with no prior AHM use) showed a non-significant 13% reduction in dementia risk with Ang-II stimulating AHMs compared to Ang-II inhibiting AHMs (aOR: 0.87, 95% CI 0.631.19, p = 0.392)